How does microneedling work? January 24, 2023 Before Dr. Downey or Dr. Bullocks begins your RF microneedling treatment, she will prep your skin by applying a topical anesthetic to your treated area, typically the face, neck and décolletage. She will then systematically press the SkinPen® microneedling device into the skin to ensure even coverage. Following your treatment, Dr. Downey or Dr. Bullocks may also saturate your skin with condition-specific serums to boost your microneedling results and promote the healing process. The entire microneedling treatment process typically takes about 30 minutes to complete.