What results and downtime should I expect after Kybella? January 24, 2023 Because Kybella® is a minimally invasive treatment, patients are able to return to their normal daily activities – including work – immediately following treatment. It is normal to experience some redness, swelling, tenderness, and bruising around your treated areas. These side effects will typically subside on their own within 24 to 48 hours of treatment. While you may see some results of their Kybella® injections after just one treatment, many patients require between three to six treatments to see ultimate results. Dr. Downey and Dr. Bullocks will determine your personalized treatment plan during your one-on-one consultation.